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if you had v2 installed on the same PC before setting up v4, then delete the contents of this folder and start DSM: C:\Users\"Your Username"\AppData\Local\SpaceClaim
This contains the config file used by DSM which may have been corrupted and prevents it from launching. Clearing it out causes DSM to generate a new config file and will open properly.
If you have just done a fresh install of any DSM version on that PC and it fails to start, it might be a different issue. Log a ticket with the support agents here (https://designspark.zendesk.com/hc/en-us/requests/new) and also attach screenshots from Windows Event viewer which are recorded for 'SpaceClaim.exe'