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What's the best impact engineers, scientists or inventors have made?

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Image source the BBC

Anyone watching the new series of The Big Life Fix on BBC? Love seeing what these modern engineers and inventors are up to, 

This got me thinking, what would I choose as the most significant and beneficial invention or development for mankind.

Fire, the wheel, electricity or something else? It's quite a hard choice as some really beneficial things have relied on other things being invented or discovered prior to their own conception.

Ok, my choice is medical, vaccination and antibiotics, they have transformed life for the better I'm sure you'll agree. But think about this, without glass, lenses couldn't be made, without lenses, we wouldn't have microscopes and without microscopes, we would never have known about the micro-bacterial life in the first place. So in my choice, glass moves to the top invention.

It's an interesting question, so if you have time please feel free to provide your answer in the comments below. 

Link to The Big Life Fix

Favourite things are Family, Music and Judo. Also, I have the ability to retain and quote useless facts, something that pleases me but can annoy others. My engineering hero - Isambard Kingdom Brunel